Jonathan Schmid-Burgk
Prof. Dr. Jonathan Schmid-Burgk
Affiliations
  • Institut für klinische Chemie und klinische Pharmakologie, Universitätsklinikum Bonn
Research topics
  • genome editing
  • innate immunity
We are developing genome-editing and sequencing technologies for studying the human innate immune system.
Selected publications

Schmid-Burgk JL*, Schmidt T*, Kaiser V, Höning K, Hornung V. A ligation-independent cloning technique for high-throughput assembly of transcription activator–like effector genes. Nat Biotechnol, 2013 Jan;31(1):76-81.

Schmid-Burgk JL, Chauhan D, Schmidt T, Ebert TS, Reinhardt J, Endl E, Hornung V. A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) Screen Identifies NEK7 as an Essential Component of NLRP3 Inflammasome Activation. J Biol Chem., 2016 Jan 1;291(1):103-9.

Schmid-Burgk JL, Höning K, Ebert TS, Hornung V. CRISPaint allows modular base-specific gene tagging using a ligase-4-dependent mechanism. Nat Commun., 2016 Jul 28;7:12338.

Schmid-Burgk JL, Gao L, Li D, Gardner Z, Strecker J, Lash B, Zhang F. Highly Parallel Profiling of Cas9 Variant Specificity. Mol Cell. 2020 May 21;78(4):794-800.e8. doi: 10.1016/j.molcel.2020.02.023.

Jonathan Schmid-Burgk
Prof. Dr. Jonathan Schmid-Burgk
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