© Volker Lannert
Dr. Katharina Scherer
Affiliations
- Institut für Mikrobiologie und Biotechnologie
- Faculty of Mathematics and Natural Sciences
Research topics
- Viruses assembly
- Dynamics of viral infection
- Fluorescence microscopy
Since March 2023, we are a new junior research group at the Institute of Microbiology and Biotechnology within the NRW Returning Scholars Programme. Our focus is to better understand viruses and their reproduction since the formation of new viral particles in the host cell is a highly complicated and crucial process for infection. High-resolution light microscopy is our preferred tool to visualise and measure the dynamics and mechanisms of virus replication. In particular, we observe how enveloped viruses efficiently assemble and disseminate new virus particles.
Selected publications
KM Scherer*, L Mascheroni* et al., SARS-CoV-2 nucleocapsid protein adheres to replication organelles before viral assembly at the Golgi/ERGIC and lysosome-mediated egress. Science advances (2022).
KM Scherer et al., A fluorescent reporter system enables spatiotemporal analysis of host cell modification during herpes simplex virus-1 replication. Journal of Biological Chemistry (2021).
L Mascheroni*, KM Scherer* et al., Combining sample expansion and light sheet microscopy for the volumetric imaging of virus-infected cells with super-resolution. Biomedical Optics Express (2020).
© Volker Lannert
Dr. Katharina Scherer