- Pharmazeutisches Institut
- Mathematisch-Naturwissenschaftliche Fakultät
- Chemical synthesis and purification of bioactive molecules
- Development of in vitro assays
- Development of radioligands, fluorescence ligands
- Stability and metabolism studies
Bhattarai S, Pippel J, Scaletti E, Idris R, Freundlieb M, Rolshoven G, Renn C, Lee SY, Abdelrahman A, Zimmermann H, El-Tayeb A, Müller CE, Sträter N (2020) 2-Substituted α,β-Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes. J Med Chem 63(6):2941-2957.
Pegurier C, Provins L, Cardenas A, Ledecq, Müller CE, Hockemeyer J, El-Tayeb A, Boshta N, Mahmoud R (2020) Pyridinyl and pyrazinyl-(aza)indolsulfonamides. WO2019243303A.
Gnad T, Scheibler S, von Kügelgen I, Scheele C, Kilić A, Glöde A, Hoffmann LS, Reverte-Salisa L, Horn P, Mutlu S, El-Tayeb A, Kranz M, Deuther-Conrad W, Brust P, Lidell ME, Betz MJ, Enerbäck S, Schrader J, Yegutkin GG, Müller CE, Pfeifer A (2014) Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors. Nature 516(7531):395-9.