© Barbara Frommann/Uni Bonn
Prof. Dr. Ulrich Kubitscheck
Zugehörigkeiten
- Clausius-Institut für Physikalische und Theoretische Chemie
- Mathematisch-Naturwissenschaftliche Fakultät
Forschungsschwerpunkte
- Nucleocytoplasmic transport
- Neuronal connectomics
- Light sheet fluorescence microscopy
- Antibiotic mode of action
Research focus is the analysis of molecular dynamics in the context of biological or biomimetical systems; especially the analysis of molecular kinetics within supra-molecular complexes at the single molecule level. We employ state-of-the-art light microscopy techniques like confocal scanning microscopy and single-molecule microscopy using different illumination techniques. A further key aspect of our work is the development of new or the improvement of existing light microscopic methods; current emphases are light sheet fluorescence microscopy (LSFM), confocal LSFM, expansion microscopy and particle tracking.
Ausgewählte Publikationen
Ruland JA, Krüger AM, Dörner K, Bhatia R, Wirths S, Pòetes D, Kutay U, Siebrasse JP and U Kubitscheck (2021) Nuclear export of the pre-60S ribosomal subunit through single nuclear pores observed in real time. Nature Comm 12(1):6211.
Baumgart E, and Kubitscheck U (2012) Scanned light sheet microscopy with confocal slit detection. Opt. Expr. 20:21805–21814.
Siebrasse JP, Kaminski T and Kubitscheck U (2012) Nuclear export of single native mRNA molecules observed by light sheet fluorescence microscopy. Proc Natl Acad Sci USA 109:9426-31.
© Barbara Frommann/Uni Bonn
Prof. Dr. Ulrich Kubitscheck