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Marcel Oberländer
© MPI Bonn
Dr. Marcel Oberländer

Website

Affiliations
  • MPI für Neurobiologie des Verhaltens - caesar
Research topics
  • decision making
  • network anatomy
  • computational modeling
The overarching goal of our research is to understand how the interplay between biophysical, synaptic, cellular and network mechanisms in the mammalian brain can encode perception and trigger behavioral responses, such as decision making during a sensory-motor task. To pursue this goal our group employs a multidisciplinary approach, combining network anatomy with cellular physiology and computational modelling. We use the whisker system of the rat for building anatomically and functionally constrained network models, and use these in silico representations of the rodent brain for predictive simulation experiments that mimic in vivo conditions, for example during sensory-guided behaviors such as texture discrimination.
Selected publications

Egger R, Narayanan RT, Guest JM, Bast A, Udvary D, Messore LF, Das S, de Kock CPJ, Oberlaender M (2020) Cortical Output Is Gated by Horizontally Projecting Neurons in the Deep Layers. Neuron 105:122-137 e128.

Rojas-Piloni G, Guest JM, Egger R, Johnson AS, Sakmann B, Oberlaender M (2017) Relationships between structure, in vivo function and long-range axonal target of cortical pyramidal tract neurons. Nat Commun 8:870.

Landau ID, Egger R, Dercksen VJ, Oberlaender M, Sompolinsky H (2016) The Impact of Structural Heterogeneity on Excitation-Inhibition Balance in Cortical Networks. Neuron 92:1106-1121.

Narayanan RT, Egger R, Johnson AS, Mansvelder HD, Sakmann B, de Kock CP, Oberlaender M (2015) Beyond Columnar Organization: Cell Type- and Target Layer-Specific Principles of Horizontal Axon Projection Patterns in Rat Vibrissal Cortex. Cereb Cortex 25:4450-4468.

Marcel Oberländer
© MPI Bonn
Dr. Marcel Oberländer

Website

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