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Nicolas Gompel
© Nicolas Gompel
Prof. Dr. Nicolas Gompel

Affiliations
  • Bonn Institute for Organismic Biology
Research topics
  • evolutionary developmental biology
  • molecular biology
  • taxonomy
My research focuses on the question of phenotypic diversity and its origin. we use the genetic model Drosophila melanogaster, and a host of related Drosophila species to tackle the genetic, molecular, cellular and developmental changes promoting trait diversification. We follow two general directions, (i) the evolution of morphology and (ii) the evolution of behavior. Our work lies at the interface of several biological disciplines: Cell and Developmental biology, Genetics, Genomics, Quantitative and Computational Biology, Phylogenetics, Population Genetics, as well as Taxonomy.
Selected publications

Ling L, Mühling B, Jaenichen R and Gompel N (2023) Increased chromatin accessibility promotes the evolution of a transcriptional silencer in Drosophila. Science Advances, 17;9(7):eade6529. doi: 10.1126/sciadv.ade6529. Epub 2023 Feb 17

Le Poul Y, Xin Y, Ling L, Mühling B, Jaenichen R, Hörl D, Bunk D, Harz H, Leonhardt H, Wang Y, Osipova E, Museridze M, Dharmadhikari D, Murphy E, Rohs R, Preibisch S, Prud’homme B* and Gompel N (2020) Regulatory encoding of quantitative variation in spatial activity of a Drosophila enhancer, Science Advances, 6(49):eabe2955. doi: 10.1126/sciadv.abe2955

Xin Y, Le Poul Y, Ling L, Museridze M, Mühling M, Jaenichen R, Osipova E, Gompel N (2020) Ancestral and derived transcriptional enhancers share regulatory sequence and a pleiotropic site affecting chromatin accessibility input, Proc Natl Acad Sci U S A, 10:202004003. doi: 10.1073/pnas.2004003117

Arnoult L, Su KFY, Manoel D, Minervino C, Magriña J, Gompel N* and Prud’homme B* (2013) Emergence and diversification of fly pigmentation through evolution of a gene regulatory module. Science, 339: 1423–1426

Nicolas Gompel
© Nicolas Gompel
Prof. Dr. Nicolas Gompel

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